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[PMC free article: PMC425362] [PubMed: 6389599] 34

Insoluble fiber adds bulk but does not dissolve in water, and it can increase gas production in a slow-moving gut

Higher-order regions, including the prefrontal cortex, hippocampus, and amygdala, are involved in evaluating external stimuli as threats (McEwen and Gianaros, 2011), while the hypothalamus serves as a key hub of neuroendocrine and autonomic regulation, initiating and maintaining the physiological stress response (Herman et al., 2016